中文摘要：

目的探讨肺小细胞癌在纤维支气管镜下的形态学特征、临床表现、病理特征以及免疫组化特点。方法回顾性分析我院2006年1月～2014年12月56例经纤维支气管镜诊断肺小细胞癌的临床病理资料。结果56例肺小细胞中男女比例为13：1，平均年龄62．3岁。免疫组化标记：CK100．0％阳性，神经内分泌标记阳性率分别为NSE87．5％。Cg—A62．5％．syn60．7％．CD5691．1％，淋巴细胞标记LCA阳性率为0。结论肺小细胞癌恶性程度高，进展迅速，病理形态有特殊表现，对神经内分泌源性抗体和上皮源性抗体标记阳性。纤维支气管镜检查是临床早期发现、明确诊断肺小细胞癌的有效方法。

英文摘要：

Objective To investigate the morphology feature, the clinical manifestation, the pathologic feature and the immunohistochemical feature in the small cell lung carcinoma which was biopsied by fibrobronchoscope. Methods The clinieopathologic data of 56 cases of the small cell lung carcinoma by fibrobronchoscope from January 2006 to December 2014 in our hospital was analysed retrospectively. Results The proportion of male to female of 56 cases lung carcinomas was 13.. 1. And the average age was 62.3 years old.The positive of CK was 100.0% which was analysised by Immunohistochemistry. The NSE, Cg-A, syn and CD56 which were neuroendocrine mark was respectively 87.5%, 62.5%, 60.7% and 91.1%. The LCA which was a lymphocytic marker was negative. Conclusion The small cell lung carcinoma was a highly malignant tumor which progressed quickly. Both the expression of neuroendocrine and epithelial markers were positive in the small cell lung carcinoma. Fiberbronchoscopy was an effective method for early detection and diagnosis of the small cell lung carcinoma.