目的:了解广西巴马地区壮族长寿家系血糖水平和血糖异常检出率情况。方法:随机抽取281个壮族长寿家系共1 973例进行空腹血糖测定,并将其结果与227个非长寿家系共1 575例的结果按年龄段和性别进行比较。结果:长寿家系的血糖总体水平,不管是男性或女性,均明显低于非长寿家系(P〈0.05或P〈0.01)。长寿家系和非长寿家系血糖水平均显示随年龄增大而呈升高的趋势(P〈0.05或P〈0.01);而长寿家系和非长寿家系之间的横向比较则显示,在30岁以后多数年龄段,非长寿家系的血糖水平比同年龄段的长寿家系高(P〈0.05或P〈0.01)。在血糖异常方面,长寿组和对照组总体之间的检出率虽无差异(P〉0.05),但亦呈现随年龄增高而检出率升高的趋势,而且非长寿家系80岁以上高龄组的血糖异常检出率明显高于长寿家系(P〈0.05或P〈0.01)。结论:巴马壮族长寿家系对血糖水平的调控有明显优势,其深层的机制值得深究。
Objective:To investigate the blood glucose level and the prevalence of hyperglycemia for the Zhuang long-lived families residing in Guangxi Bama area.Methods:Fasting blood glucose was tested and the incidence of hyperglycemia was calculated for 281 long-lived families including 1 973 individuals and 227 non-long-lived families with 1 575 members.Then glucose levels and hyperglycemia were compared between the long-lived and the control group according to different age subgroup and gender.Results:The blood glucose level,both in men and women,in long-lived families was significantly lower than that in the non-long-lived controls.An increasing trend of blood glucose with age was observed in both long-lived and non-long-lived families.Furthermore,the blood glucose levels in non-long-lived families in most age subgroup beyond 30 years old were remarkably higher than those in the long-lived families.The incidence of hyperglycemia was also shown a raising tendency with age both in long-lived and non-long-lived families although no great preference difference was found between the two family groups.However,higher hyperglycemia rate was found in non-long-lived families than in long-lived ones in age 80 and older.Conclusion:Bama long-living families have prominent advantage in regulating blood glucose level.Its underling mechanism needs further investigation.