中文摘要：

目的 同向易化视觉现象被认为是发生在中央视野、以视觉皮质邻近神经元间相互作用为基础的一种视觉信息加工过程,表现为对目标物单独出现时的察觉能力低于其周边伴有同向干扰物时。基于原发性开角型青光眼（POAG）的发病机制,观察该现象在此人群中的行为特性改变。方法 选取4组受试者,分别为视野损害青光眼组、视野损害前青光眼组和各自的正常对照组。4组分别在目标刺激（正弦光栅）单独出现时以及伴有不同间隔距离的干扰刺激（正弦光栅）时,进行对比度察觉任务并获得对比敏感度。结果 随着目标刺激与干扰刺激间隔距离的增大,所有受试者的对比敏感度受同向易化的影响减小;视野损害和损害前青光眼受试者的对比敏感度受同向易化影响的范围较正常组明显增大了2λ和4λ（λ为光栅波长）。结论 POAG中同向易化视觉现象影响范围发生了增大的行为改变,且可发生在视野损害以前。（中国眼耳鼻喉科杂志,2017,17：176-179）

英文摘要：

Objective Collinear facilitation is considered as a phenomenon in the fovea characterized by the interaction of visual cortical neurons. Such facilitation is found when the target is presented simultaneously with collinear similar flankers rather than it is solely presented. Behavioral characteristics of collinear facilitation were investigated in primary open-angle glaucoma （POAG） on the basis of its pathogenesis. Methods Contrast sensitivities （the reciprocal of contrast threshold） of POAG with little or much visual field loss and normal controls were acquired in the contrast detection tasks, which involved single sinusoidal grating and sinusoidal grating with collinear flankers. Results Collinear facilitation became weaker along with larger distance between target and flankers through all groups. Moreover, the range had statistically expanded 2k and 4k, respectively in POAG either with little or much visual field loss than controls. Conclusions The range of collinear facilitation was found to be enlarged in POAG, even before visual field had emerged damage. （ Chin J Ophthalmol and Otorhinolaryngo1,2017,17 ： 176-179 ）