木质纤维素是自然界最丰富的可再生资源,含有大量的碳水化合物。自水解/稀酸水解是木质纤维酶解糖化和生物转化高附加值产品的重要预处理手段。水解过程中碳水化合物解聚溶解转化成可发酵糖,但目前所采用的水解预处理方法中,同时还会产生一些低分子发酵抑制性物质,一般包括低分子有机酸、糠醛类和溶解性酚类物质等,这些抑制物严重影响了微生物对水解产物的发酵活性,从而大大降低了发酵目标产物的得率。本文对木质纤维素水解过程中发酵抑制性物质的产生途径和影响因素,发酵抑制物的种类与抑制机理,以及目前对这类物质的脱毒方法进行了综述和前景展望。
Lignocelluloses is one of nature's most abundant renewable resources, and it contains a large number of carbohydrate components. Autohydrolysis/Dilute acid hydrolysis is important pretreatment methods that lignocelluloses enzymatic saccharify and produce high value-added products by a way of bioconversion. Carbohydrate is depolymeized and converted into fermentable sugars in the process of hy- drolysis. But in various kinds of pretreatment method, always produce some fermentation inhibitor, in- cluding low molecular organic acids, furfural and soluble phenols content. The fermentation inhibitor se- riously affected the microbial fermentation of hydrolysis, thereby significantly reduces the yield of the fermentation. In this paper, the fermentation inhibitor of lignocelluloses hydrolysis, type, inhibition mechanism and the process of removal methods were summarized, and the detoxification of fermentation inhibitor development orospects were discussed.