目的:探讨轻度隧性乙型肝炎(CHB)患者的中医证候分布规律,为规范化治疗CHB提供参考依据。方法:运用中医证候量表对594例轻度CHB患者进行中医证候调查,采用聚类分析的方法对纳入的患者进行聚类,并结合变量频数分析对证型归属进行判定。结果:收集的轻度CI-IB病例均以肝郁脾虚为主要证型,在此基础上合并有6个兼证,分别为肝郁脾虚兼湿热阴虚血瘀证型(6280%)、肝郁脾虚兼肝肾阴虚证型(24.24%)、肝郁脾虚兼肝郁化火证型(5.05%)、肝郁脾虚兼肝胃不和证型(3.70%)、肝郁脾虚兼中气亏虚证型(253%)和肝郁脾虚兼瘀血阻络证型(1.68%)。肝郁脾虚兼湿热阴虚血瘀证型又进一步分为5个亚型,分别为脾虚为主型(45.30%)、普通型(22.52%)、气滞为主型(17.70%)、湿热为主型(1Q46%)、肾虚为主型(402%)。
Objeclive: To discuss the distribution law of the traditional Chinese medicine (TCM) syndrome in mild chronic hep- atitis B, and provide the evidence to standardize treatment of chronic hepatitis B. Methods: Five hundred ninety-four patients with chronic hepatitis B were collected, the TCM syndrome was judged by the scale of the TCM syndrome, and the identification patterns were determine by the distribution of variables using duster analysis. Results: The main identification pattern of mild chronic hepatitis B was liver stagnation and spleen deficiency. There were six accompanying syndromes within the main pattern, damp heat - Yin defi- ciency and blood stasis syndrome (62. 80% ), Yin deficiency of liver and kidney syndrome (24. 24% ), depressed liver Qi transfor- ming into fire syndrome (5. 05% ), liver and stomach incoordination syndrome (3. 70% ), Qi deficiency syndrome (2. 53% ), blood stasis syndrome ( I. 68% ), and the liver stagnation and spleen deficiency accompanying damp heat - Yin deficiency and blood stasis syndrome also included five subtypes, spleen deficiency syndrome (45. 30% ), usual syndrome (22. 52% ), Qi stagnation syndrome ( 17. 70% ), damp heat syndrome ( 10. 46% ), kidney deficiency syndrome (4. 02% ) . Conclusion: The main identification pattern of mild chronic hepatitis B is liver stagnation and spleen deficiency.