microRNA(miRNA)是调节生物体发育的有效分子,表现为对基因的微量调节。现有的证据表明miRNA参与天然免疫和适应性免疫应答的调节,这种调节与免疫系统发挥作用有十分密切的关系。因此,对miRNA的研究有助于对人类免疫系统调节机制更深入地了解,建立基于miRNA的有效疗法。
microRNAs function as effective molecules in regulation of many biological functions of organisms;in most case they regulate gene expression moderately.Emerging evidence suggests that microRNAs play a key role in the regulation of immunological functions including innate and adaptive immune responses.The research on microRNAs would be helpful in elucidation of the mechanisms of human immune system and in development of potential therapies based on microRNAs.