通过合理改性来调控淀粉的消化性能,使其具有不被上消化道消化、但能够被结肠微生物酵解的特性,则可用作口服结肠靶向药物控释载体。综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景。
Starch can not be digested in the upper gastrointestinal but can be microbially decomposed in colon by suitable modifications which control starch digestibility, thus it can be used as carrier for oral colon-specific drug delivery system. This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system.