中文摘要：

目的 研究热风-微波联合干燥方法加工当归药材的可行性,并对加工药材进行质量评价研究。方法 分别对热风干燥温度、热风干燥时间、微波干燥电流、微波干燥时间进行考察,根据《中国药典》2015年版当归项下指标对加工药材进行质量评价,结合微生物数量和产能,选出最优工艺;分别检测最优工艺加工样品、硫熏样品和阴干样品的微生物数量、重金属及有害元素量和10种活性成分（阿魏酸、阿魏酸松泊酯、洋川芎内酯I、洋川芎内酯H、洋川芎内酯A、E-藁本内酯、Z-藁本内酯、正丁烯基苯酞、riligustilide、欧当归内酯A）量。结果 最终确定热风（70℃）干燥20 h＋微波（100 m A）干燥6 min为最优工艺。经新方法加工的样品微生物数量与硫熏样品相当,所加工样品重金属及有害元素均未超标,并且对药材活性成分无显著影响。结论 经新方法加工的当归药材各项理化指标均符合《中国药典》2015年版规定,热风-微波联合干燥技术可以作为当归药材产地加工中的一种快速干燥方法。

英文摘要：

Objective In this study, the feasibility of hot air-microwave combination drying method for processing Angelicae Sinensis Radix （ASR） was investigated and evaluated. Methods Hot air temperature, drying time, microwave electric current, and microwave time were taken into consideration. The combined drying method was optimized based on the standards of ASR documented in Chinese Pharmacopoeia （2015 version）. After that, microorganisms, heavy metals, harmful elements, and active ingredients （ferulic acid, coniferyl ferulate, senkyunolide I, senkyunolide H, senkyunolide A, E-ligustilide, Z-ligustilide, n-butylidenephthalide, riligustilide, and levistilide A） were detected to evaluate the quality of processed samples. Results The optimal method was that samples were dried in hot air （70 ~C） for 20 h, then heated in microwave （100 mA） for 6 rain. The number of microorganisms in processed samples equaled to sulfur-fumigated samples; Heavy metals and harmful elements were qualified after this processing; The new drying method for processing ASR had no significant effect on the active ingredient, Conclusion After this process, the physical and chemical indicators of ASR are in line with the criteria of Chinese Pharmacopoeia. This hot air-microwave combination drying method should be a fast drying method for post-harvest handling of ASR.