中文摘要：

现有关于脾主运化的认识只强调了脾的消化吸收功能，而脾转化散精的功能研究甚少。随着生活方式和疾病谱改变，作为脾虚证特殊表现形式的脾虚不化证日益增多，其典型病症就是目前发病率不断上升的代谢综合征（MS）及其因子疾病。文章系统整理有关脾主运化理论的论述，结合现代医学研究和临床实践，提出完整脾主运化的功能应包括消化、吸收、输布和气化4个方面，脾主运和脾主化是2个不同概念；从发病的社会背景、证候属性以及治则治法对脾虚不运证和脾虚不化证加以区分；提出将MS作为脾虚不化证的代表病种、以胰岛素抵抗（IR）为切人点，阐明IR状态下脾虚不化的证候特点，丰富脾主运化的脏象学说理论，为防治MS及其因子疾病提供科学依据。

英文摘要：

The current understanding of the function of spleen controlling transportation and transformation only emphasized the digestion and absorption functions of the spleen, with little study on function of spleen transformation. Along with the change of lifestyle and diseases, as a special manifestation of the spleen deficiency syndrome, the incidence of spleen transformation deficiency syndrome was increasing; typical diseases were metabolic syndrome （MS） whose incidence raised frantically and its factor disease. On the basis of literature research and clinical practice, this paper clearly stated the integrity function of spleen controlling transport and transformation, which included digestion, absorption, transmission and distribution and gasification four aspects. The function of transport and transformation was divided into two different concepts. From the incidence of social background, syndrome properties and therapeutic principle, spleen transport deficiency syndrome and spleen transformation deficiency syndrome were clearly distinguished. We made the MS as the representative disease of the spleen transformation deficiency syndrome, insulin resistance （IR） as the starting point. This study clarified characteristics of the spleen transformation deficiency syndrome with IR, and enriched the theory of spleen functions controlling transport and transformation.