中文摘要：

杯芳烃对客体具有优异的识别作用，可作为毛细管电泳的添加剂,以R-和s-联萘酚（BINOL）为溶质探针，优化获得了R-和S-BINOL毛细管电泳的分离条件，用量子化学计算辅助研究了磺酸基杯[6]芳烃（SCx6）在电泳分离R-和s-联萘酚中的作用．结果表明，在电泳溶液为25mmol·L^-1醋酸铵＋10mmol·L^-1 SCx6的乙腈-水（6：4，v／v）（pH8．75）、运行电压为＋30kV、检测波长为335nm的条件下，R-和S—BINOL在48．5cm（有效长度40cm）×50μm石英毛细管内可实现部分分离．用所建立的DFT—B3LYP／3—21＋G^＊量化计算方法，获得了溶质R-和S-BINOL与SCx6形成的S-BINOL—SCx6、R—BINOL—SCx6超分子结构，直观地观察到了BINOL与SCx6之间的叮π-π疏水作用和氢键作用．超分子S-BINOL—SCx6、R—BINOL—SCx6的△G数值、稳定性与其电泳行为一致．

英文摘要：

In this paper, the migration behaviors of axially chrial R- and S- binaphthol （BINOL） without symmetric carbon center by capillary electrophoresis （CE） using p -sulfonate calix[ 6 ] arene （SCx6） as the ad- ditive are reported. The influence of electrolyte concentration, SCx6 concentration, solvent and pH value of the running buffer on the separation of R - and S - BINOL is investigated. An increase of SCx6 concentration up to 10 mmol · L^-1 in the CE running buffer, R - and S - BINOL achieves a partial separation. The addition of SCx6, forming different supramolecular complexes with R - and S - BINOL, facilitates their separation. The supramolecular interaction mechanism is discussed through the quantum chemistry calculation using DFF -B3LYP/ 3 -21 ＋ G^＊ as the base group.