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中文摘要：
使用SiC管为反应容器, 在微波辐射条件下以[（η^6-C6H6）RuCl2]2为原料与2-（吲哚基）咪唑[4,5-f]-[1,10]菲啰啉（H2iiP）反应, 制得芳烃钌（Ⅱ）化合物Cl[（η^6-C6H6）Ru（H2iiP）Cl]Cl（1）, 并对其进行了表征. 采用正交实验法确定反应的最佳合成条件为： 投料比n（[（η^6-C6H6）RuCl2]2）： n（H2iiP）=1： 2.2, 反应温度90℃, 微波辐射时间30 min. 该反应的平均产率达到96.0%, 反应产率的相对标准偏差（RSD）为1.28%, 说明微波辐射条件下, 在SiC管中能够高产率地制备芳烃钌化合物, 并且反应具有良好的重现性. 进一步采用MTT方法研究发现, 芳烃钌（Ⅱ）化合物1能够选择性抑制MCF-7乳腺癌的生长.
英文摘要：
Arene Ru（Ⅱ） complex [（η^6-C6H6）Ru（H2iiP）Cl]Cl（1） was synthesized using [（η^6-C6H6）·5RuCl2]2 and 2-indole-3-imidazole[4,5-f][1,10] phenanthroline（H2iiP） as raw material under microwave irradiation. The target compound was characterized by means of elemental analysis, ESI-MS, IR and NMR. The best craft condition determined by orthogonal test is that reactant molar ratio of 1.0： 2.2, the reaction tempe-rature of 90℃ and the microwave irradiation time of 30 min. Then the average yield of 96.0% and RSD of 1.28% confirmed that microwave-assisted synthesis of arene Ru（Ⅱ） complex in SiC vessel gives a good stability and reiteration. The antitumor activity of arene Ru（Ⅱ） complex 1 was determined by MTT assay and the results showed that complex 1 could selectively inhibit the growth of MCF-7, indicating its potential utility in chemotherapy.
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