中文摘要：

高效抗逆转录病毒治疗（HAART）对控制HIV-1进展效果显著，但病毒潜伏库的存在导致病毒无法完全清除。HIV-1感染后，潜伏库建立早，半衰期长，长期处于静息状态，是根治HIV-1感染的主要障碍之一。目前清除病毒潜伏库的方法有潜伏感染激活剂、免疫治疗和基因治疗等。此文主要讨论了HIV-1潜伏感染激活剂相关内容。

英文摘要：

Highly active antiretroviral therapy （HAART） is effective in controlling HIV-1. However, due to the existence of viral reservoirs, HIV-I can＇t be eliminated completely. The viral reservoir is established in the early stage of infection, possessing a very long half-life and staying quiescent most of the time, which is the major problem to the cure. Nowadays, the possible ways to eradicate HIV-1 are latent infection activator, immune-based therapies, gene therapy approaches and so on. The latent infection activator of HIV-1 is discussed in this article.