欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
颅脑损伤(traumatic brain injury,TBI)是现代社会中的常见疾病,治疗存在难题,严重影响人类的生存质量.在颅脑损伤后的早期脑损伤(early brain injury,EBI)期间继发的病理生理级联中,活性氧簇(reactive oxygen species, ROS)快速反应,通过对脂质、蛋白与核酸的急性与持续损伤,在EBI发病机制、神经退行性变及其预后中发挥重要作用.但目前EBI急性氧化损伤研究方法中,普遍存在ROS等应激反应快而研究选择时间点滞后的问题,这与EBI发生的反应速度快、影响大的特点相悖,影响对TBI发病机制的精确掌握.
同期刊论文项目
同项目期刊论文
A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality cont
Simultaneous quantitation of seven anthraquinones in aqueous extract of rhubarb and analysis for abs
Pharmacokinetic study of the prokinetic compounds meranzin hydrate and ferulic acid following oral a
Enhanced antitumoral efficacy and immune response following conditionally replicative adenovirus con
Fructus Aurantii induced antidepressant effect via its monoaminergic mechanism and prokinetic action
Ferulic acid-induced anti-depression and prokinetics similar to Chaihu-Shugan-San via polypharmacolo
Pharmacokinetic comparison of ferulic acid in healthy volunteers and patients with functional dyspep
Meranzin Hydrate Induces Similar Effect to Fructus Aurantii on Intestinal Motility through Activatio
Meta-analysis of the clinical effectiveness of traditional Chinese medicine formula Chaihu-Shugan-Sa
Meranzin hydrate exhibits anti-depressive and prokinetic-like effects through regulation of the shar
The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokine
期刊信息
位置：