病毒性心肌炎是一种常见的感染性疾病,在急性期常因起病隐匿而以猝死为首要表现;恢复期和慢性期则伴有明显的心肌纤维化,部分患者最后进展为扩张型心肌病和严重的充血性心力衰竭。多种因素参与心肌纤维化,本文就这些影响因素的相互作用及如何调控纤维化的发生发展机制作一综述,为临床上心肌炎的防治提供理论依据。
Viral myocarditis is a common infectious disease, which always appeared as sudden unexpected natural death for its hiding onset. The heart of patients always had a fibrosis at the recovery or chronic period. Some people developed into dilated cardiomyopathy at last. This article reviewed present progression of the cardiac collagen net-work(CCN) ,changes of the CCN in viral myocarditis and the influence factors.