中文摘要：

目的运用MRI评价多条颅神经的形态学异常改变，分析其对斜视病因诊断的价值。设计回顾性病例系列。研究对象55例斜视患者。方法患者行MRI检查，采用3DFIESTA序列，分析脑池段颅神经的MRI表现。主要指标脑池段颅神经的发育情况。结果观察所有55例患者多对颅神经脑池段，发生颅神经异常的MRI表现包括：21例眼外肌纤维化综合征者中，脑池段动眼神经2条未显示，38条动眼神经纤细；16例双侧眼球后退综合征、15例眼外肌纤维化综合征和3例眼一面麻痹综合征中，脑池段外展神经41条未显示，19条纤细，2条脑池段外展神经走行区纤细索条影，1条起始位于脑干中部，1条走行区只见不规则形索条影。3例眼一面麻痹综合征和6例眼球后退综合征患者中，6条面神经、6条听神经、3条舌下神经脑池段未显示。结论MRI能够清晰显示颅神经脑池段的异常改变，为神经源性斜视的诊断提供客观依据。

英文摘要：

Objective The abnormalities of cranial nerves in the cistern were displayed by MRI to explore their relationship with strabismus. Design Retrospective case series. Participants Fifty-five patients with strabismus. Methods Fifty-five patients were per- formed MRI examination, using three dimensional fast imaging employing steady state acquisition （FIESTA） sequence. Cranial nerves in the cistern were observed in oblique-axial and oblique-sagittal planes acquired by MRI. Main Outcome Measures The developmental conditions of the cranial nerves in the cistern. Results All the abnormal cranial nerves in the cistern in 55 cases on MRI were dis- played as follow. In 21 cases of congenital fibrosis of extraocular muscles （CFEOM）, 2 oculomotor nerves （CN3） were absent and 38 were thinner. In 16 cases of Duane syndrome （DS）, 15 cases of CFEOM and 3 cases of Mobius syndrome, 41 abducens nerve were ab- sent, 19 were thinner, 2 were chords-like signs, 1 was starting from the middle part of the brainstem, and 1 was substituted by an irreg- ular chords-like signs. Other cranial nerves in the cisterns could not be traced including 6 facial nerves, 6 audible nerves and 3 hy- poglosssal nerves in 3 cases of Mobius syndrome （MS） and 6 cases of DS. Conclusion MRI can clearly demonstrate abnormality of cra- nial nerves in the cistern, which can be used for the diagnosis and differential diagnosis of neurogenic strabismus.