中文摘要：

胰腺神经内分泌肿瘤（pNENs）分为功能性与无功能性两大类,常见类型包括胰岛素瘤、胃泌素瘤、胰高血糖素瘤、血管活性肠肽瘤等,根治性手术切除是pNENs患者治愈和长期生存的唯一方法.基本手术方式包括局部切除和规则切除两类,前者为肿瘤局部切除（剜除）术,后者包括胰十二指肠切除术（标准或保留幽门）、胰体尾切除术（联合脾脏切除或保留脾脏）及中段胰腺切除术等.肝脏是最常见远处转移部位,手术切除是肝转移瘤首选治疗方法,RFA、TACE以及肝移植可以作为辅助治疗手段.

英文摘要：

Pancreatic neuroendocrine neoplasms （pNENs） can be divided into functional and non-functional.Insulinomas,gastrinomas,glucagonomas and VIPomas are the common types of pNENs.Radical resection is the only way for curing pNENs or for a long-time survival of patients.The basic surgical procedures for pNENs are consist of local resection （tumor enucleation） or anatomical resection [pancreatoduodenectomy （standard or pylorus-preserving pancreatoduodenectomy）,distal pancreatectomy （combined with splenectomy or spleen-preserving pancreatectomy） and middle segmental pancreatectomy].Liver is the most common site for metastases.Surgical resection is the method of choice for liver metastases.Radiofrequency ablation,transcatheter arterial chemoembolization and liver transplantation could be the adjunctive therapies.