中文摘要：

建立HPLC法同时测定舒肝健胃丸中五种成分（芍药苷、柚皮苷、橙皮苷、和厚朴酚与厚朴酚）含量的方法．采用高效液相色谱法，色谱柱为TC-C18（4．6mm×250mm，5μm），检测波长为0～10min，230nm，10～20min，283nm和20-55min，294nm；流动相为乙腈-水溶液，梯度洗脱0～15min，22％～22％；15～25min，22％～72％；25～35min，72％-72％；35～40min，72％-90％；40～50min，90％-90％；50～55min，90％～22％；流速为1．0mL·min^-1；柱温为25℃．芍药苷、柚皮苷、橙皮苷、和厚朴酚与厚朴酚的质量浓度分别在0．672～67．2mg·mL^-1、3．124～312．4mg·mL^-1、2．3712～237．12mg·mL^-1、0．44～440mg·mL^-1和1．196^-1～119．6mg·mL^-1范围内呈良好的线性关系．测定舒肝健胃丸中芍药苷、柚皮苷、橙皮苷、和厚朴酚和厚朴酚的含量分别为0．68mg·g^-1、2．85mg·g^-1、6．75mg·g^-1、1．09mg·g^-1和1．09mg·g^-1本方法简单方便、准确可靠、专属性强，为舒肝健胃丸药品的质量控制提供了方法依据．

英文摘要：

To establish an HPLC method for simultaneously determining five components such as paeoniflorin, naringin, hesperidin, magnolol and honokiol in Shugan Jianwei pills by HPLC. An RP-HPLC method was established with TC-C18 （4.6 mm×250 mm,5 μm）column. Detection wavelengths were set at 230 nm between 0 and 10 min,283 nm between 10 and 20 min,and 294 nm between 20 and 55 min,respectively. The mobile phase was acetonitrile-water with a gradient program （0 -15 min,22% -22% ;15 -25 min,22% -72% ;25 - 35 rain ,72% - 72% ;35 -40 min ,72% - 90% ;40 - 50 min ,90% - 90% ;50 - 55 min,90% - 22% ）. The flow rate was 1 mL · min-1. The column temperature was 25 ℃. There was a good linearity between the absorption peak area and the concentration for paeoniflorin, naringin, hesperidin, magnolol and honokiol in the ranges of 0. 672 -67.2 mg · mL^-1 ,3. 124 -312.4 mg · mL^-1 ,2. 3712 -237.12 mg· mL-I ,0.44 -440 mg·mL^-1 and 1. 196- 119. 6 mg · mL^-1, respectively. The contents of paeoniflorin, naringin, hesperidin, magnolol and honokiol in Shugan Jianwei pills were 0.68 mg·g^-1,2.85 mg · g^-1,6.75 mg·g^-1,1.09 mg·g^-1 and 1.09 mg ·g^- 1 ） respectively. The method is accurate, sensitive, reliable, and with good reproducibility, which provides a reference for the quality control of Shugan Jianwei pills.