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胰酶-EDTA差速消化法纯化原代培养的汗腺细胞
  • 期刊名称：感染、炎症、修复
  • 时间：2013
  • 页码：225-227
  • 分类：R394[医药卫生—医学遗传学;医药卫生—基础医学]
  • 作者机构：[1]解放军总医院生命科学院,北京100853, [2]北京军区总医院药理科,北京100700, [3]解放军总医院第一附属医院全军创伤修复与组织再生重点实验室暨皮肤损伤修复与组织再生北京市重点实验室,北京100048
  • 相关基金：国家“973”计划资助项目（2012CB518105）;国家自然科学基金资助项目（81121004,81230041,81171798）
  • 相关项目：去分化源性表皮干细胞的特征、种属差异及在皮肤创伤修复中的应用研究
作者： 孙同柱|马奎|张翠萍|付小兵|
关键词： 临床应用, 微小RNA, 治疗, 实验室, MIRNAS, 非编码小RNA, 人类基因组, MIRNAS
中文摘要：

微小RNA（miRNA）是由18～24个核苷酸组成的单链非编码小RNA。研究预测，人类基因组中超过60％的基因受miRNAs调节．miRNAs在各种生理、病理过程和疾病治疗中发挥着重要作用。作为分子生物领域一个新的研究热点，当前miRNAS的研究发展迅速，获得了重要的研究进展，但miRNA研究仍处于早期阶段，尤其面向临床应用时，许多现实问题和技术性瓶颈仍有待于解决。

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诱导间充质干细胞重编程为汗腺样细胞再生汗腺的关键信号途径及分子机制研究
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严重创伤机体重要组织和器官损伤修复与再生研究
期刊论文 129 获奖 10 著作 10
去分化源性表皮干细胞的特征、种属差异及在皮肤创伤修复中的应用研究
期刊论文 34 获奖 1 著作 1
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