目的 研究老年男性缺血性心血管疾病发病情况及相应的干预措施.方法 准确记录2003年10月~2009年10月北京地区某医院数据库记录在案的年龄>65岁,无ICVD病史的所有老年男性.记录其一般信息,吸烟史,体重指数、收缩压、血总胆固醇浓度、血甘油三酯浓度、血高密度脂蛋白-胆固醇浓度、血肌酐浓度、血载脂蛋白A1浓度、空腹血糖等相关指标,连续监测目标人群研究期间的ICVD累计发病率,并使用Logistic多元回归分析进行危险因素筛查,寻找其防治的环节.结果 2 123例老年男性,6年内ICVD累计发病率为23.5%.Logistic多元回归分析结果显示:高收缩压、空腹血糖升高、体重超标是最主要的危险因素.结论 ICVD在老年保健人群中呈高发病率.降低未来ICVD事件措施应包括:严格控制血压,降低血糖,控制体重.
Objective To analyze the incidence and risk factors of ischemic cardiovascular disease (ICVD) in the elderly male population and seek solution for the prevention and effective treatment. Methods The analysis was performed on those 65-year old patients who visited the hospital in between May 2003 and October 2009. 2123 over 65-year patients who had no ICVD history were selected for the 6-year continuing follow-up study. Their physical examination, smoking history, body mass index (BMI), systolic blood pressure (SBP), serum creatinine level (Scr), serum total cholesterol level (TC), high density lipoproteins-C (HDL-C), fasting blood glucose level (FBG) were monitored, and the cumulative incidence of ICVD was recorded. Logistic regression hazard model were applied to analyze the risk factors for ICVD among this elderly male population. Results The 6-year cumulative incidence of ICVD among the 2123 elderly male population was 23.5%. Multivariate analysis showed that high SBP, FBG, BMI were considered as main risk factors. Conclusion The incidence of ICVD is high in the elderly male population. The preventive measures may include controlling blood pressure, blood glucose, as well as controlling body weight.