中文摘要：

目的确定成人大骨节病指骨X线损害的特异性标志，为提高成人大骨节病临床诊断和疗效判定提供重要科学依据。方法采用现况调查设计重复阅片法，应用《大骨节病X线分型分度判定》（WS／T207—2001）与自行设计的成人大骨节病掌指骨损害评分法阅读同一例成人大骨节病患者手部X光片。应用多元线性回归分析筛选两种大》骨节病X线评价方法与临床体征的相关性及其特异性损害特征。结果3种评价方法的相关系数分别为0．568、0．621、0．856，具有统计学意义。多元线性回归分析筛选出一、二指骨的关节增粗及其指间关节间隙狭窄是成人大骨节病损害最显著的部位和X线征象。站论第一、二指骨的关节增粗和关节间隙狭窄是成人大骨节病手部损害显著的X线变化。

英文摘要：

Objective To evaluate the characteristics of specific X-ray damage on adults hands of KBD, so as to provide significant scientific foundation for the clinical diagnosis and treatment on KBD. Methods Based on the traditional duplication radiographic reading method and WS/T 207-2001, as well as the self-designed adult KBD Metacarpophalangeal damage score table, the experimenter read all of the X-ray films by three diagnostic criteria in different phases. Each of subjects was conducted with a questionnaire survey, clinical＇ examination and taken an X-ray film of right-hand. The questionnaire includes： basic information, clinical symptoms, and the scale by Chinese X-ray diagnostic criterion, K-L assessment, through the multiple linear regression analysis of hand to confirm the specific X-Ray characteristics. Results The correlation coefficients of three assessments of KBD are 0. 568, 0. 621 and 0. 856 respectively, with statistical significance~ The specific X-Ray characteristics of the hand of adult KBD are the second finger, the third finger, carpal, joint thickening, joint space narrowing. Conclusion The specific damage characteristics of adult KBD patients are joints thickening and joint space narrowing in the second finger, the third finger and carpal.