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中文摘要：
利用两亲性线性-超支化多臂共聚物聚乙二醇-聚乙烯亚胺-聚谷氨酸苄酯（PEG—PEI—PBLG）在水溶液中自组装为阳离子囊泡．利用透射电镜、动态光散射、静态光散射和zeta电位仪对囊泡结构进行了表征．PEG—PEI—PBLG囊泡具有双分子层结构，壁厚5～10nm，直径在100nm左右．由于PEI在水溶液中的质子化作用，囊泡表面携带有正电荷，其表面电势为＋25．2mV，因此PEG—PEI—PBLG阳离子囊泡具有担载负电性蛋白的能力．
英文摘要：
Amphiphilic linear-hyperbranched multi-arm copolymer poly（ ethylene glycol）-polyethyleniminepoly（T-benzyl L-glutamate）（PEG-PEI-PBLG） can self-assemble into cationic vesicles in aqueous solution. TEM, DLS, SLS and zeta potential measurement were used to characterize the structure of the PEG-PEI-PBLG vesicles. The vesicles were constituted of 5-10 nm bimolecular layers with average diameter in 100 nm and surface zeta potential of ＋ 25.2 mV. The positive charges on vesicles surface were caused by the protonation of PEI in aqueous solution. The cationic vesicles have an ability to carry negatively charged proteins.
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