回顾性分析107例男性催乳素腺瘤患者治疗前垂体功能减退的特点。发现该组患者生长激素轴和性腺轴减退发生率最高;且对于大腺瘤(〉1em)患者,瘤体直径增大和高催乳素血症并不明显增加垂体功能减退的发生率,但其可作为判断减退程度的指标之一。
Base on pretreatment clinical data of 107 patients, we retrospectively characterized hypopituitarism adult men harboring prolactionomas. The incidence of growth hormone deficiency and hypogonadism is the most common pattern. As to adult males harboring macroprolactinomas ( 〉 1 cm), maximal adenoma diameter and higher prolactin level are no more the primary factor causing hypopituitarism, but affecting the degree of hormone insufficiency.