中文摘要：

目的探讨初诊2型糖尿病患者铁负荷的变化。方法初诊2型糖尿病患者30例及健康对照者32例,采用酶联免疫法检测血清铁蛋白（FT）、转铁蛋白（TRF）水平,采用生化法检测空腹血浆葡萄糖、血清铁（Fe）、铁总结合力（TIBC）、血脂水平。结果2型糖尿病血清FT水平显著高于健康对照组（P〈0.05）,但两组间血清Fe、TIBC、TRF、TRF饱和度（TS）水平差异无显著性（P〉0.05）。血清FT与血糖呈显著正相关,与高密度脂蛋白呈显著负相关。结论初诊2型糖尿病患者存在明显铁超载,但铁超载在2型糖尿病发病过程中的作用还有待于进一步研究。

英文摘要：

Objective To explore changes of iron load in newly diagnosed type 2 diabetic patients.Methods 30 newly diagnosed type 2 diabetics and 32 healthy control subjects were observed prospectively.The serum ferritin and transferrin values level were determined with ELISA method.The Plasma glucose,serum iron,TIBC and lipid level were determined with bio-chemistry method.Results The serum ferritin level were higher than baseline and there were statistics significantly differences between two groups（P〈0.05）.But There were no statistics significantly differences in the serum iron,TIBC,transferring and transferring saturation level between two groups（P〉0.05）.FT compared with plasma glucose were positive relativity and FT compared with HDL-C were negative relativity.Conclusion Newly diagnosed type 2 diabetic patients have significant iron excess.But its role in newly diagnosed type 2 diabetics needs further research.