中文摘要：

从黄花蒿内生菌Myrothecium roridum IFB-E091固体发酵产物中分离获得3个化合物,分别被鉴定为：（S）-（-）-N-[2-（3-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl）-ethyl]-acetamide（1）、N-（4-hydroxyphenethyl）acetamide（2）和asperfumoid（3）,其中化合物1为新吲哚衍生物。体外细胞毒活性测定表明,化合物1对人肝癌细胞SMMC-7721和人宫颈癌细胞He La没有明显的抑制活性。

英文摘要：

Three compounds were isolated from solid culture of endophyte Myrothecium roridum IFB-E091 in Artemisia annua. Their structures were determined as （S）-（-）-N-[2-（3-hydroxy-2-oxo-2,3-dihydro-1H-indol- 3-yl）-ethyl]-acetamide （1）, N-（4-hydroxyphenethyl）acetamide （2） and asperfumoid （3）, in which compound 1 was a new indole derivative. In cytotoxicity assay, the compound 1 had no obvious inhibition activity in human hepatoma cell line SMMC-7721 and human cervical carcinoma cell line HeLa.