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中文摘要：
我们描述了合成一系列(芳基醚) poly，在核心和 oligo (环氧乙烷) 的 dendrimerswith 碲化物在作为谷胱甘肽，过氧物(GPx ) 模仿行为的圆周锁住。这些混合物的系列被 ~ 1H-NMR， ~(13 ) C-NMR 和 ESIMS 很好描绘。用不同 ROOH (H_2O_2，茴香素水疗院过氧化物) 因为测试这些的 theantioxidizing 性质加重，我们发现了从产生 0 ～ 2，树枝状的 GPx 的活动模仿第一减少然后增加。这能根据更大的位阻现象被解释，从产生 0 ～ 1 去，并且更强壮的有约束力的相互作用从产生 1 ～ 2 去。换句话说，在那里存在在可以优化 GPx 活动的有约束力的相互作用和位阻现象之间的平衡。
英文摘要：
We have described the synthesis of a series of poly（aryl ether） dendrimers with telluride in the core and oligo（ethylene oxide） chains at the periphery which act as glutathione peroxidase （GPx） mimics. These series of compounds were well characterized by ^1H-NMR, ^13C-NMR and ESI-MS. Using different ROOH （H2O2, cumene hydroperoxide） for testing the antioxidizing properties of these compounds, we have found that from generation 0 to 2, the activity of the dendritic GPx mimics first decreased and then increased. This can be explained on the basis of a greater steric hindrance, going from generation 0 to 1, and stronger binding interactions going from generation 1 to 2. In other words, there exists a balance between binding interactions and steric hindrance that may optimize the GPx activity.
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