近年来中药药理研究成果丰硕,不少传统中药的有效成分、作用机制等均已明确,尤其是在针对现代疾病的治疗上,中药药理学研究提供了明确的证据。然而,目前大多数药理学研究成果并未有效地应用于临床研究,中药药理学研究与中医临床基本处于脱节状态。尽管有不少临床医师已开始有意识地应用药理研究成果,但多数临床处方基本是研究成果的简单叠加。而药理研究成果的临床回归首先不能背离中医理论,应当是在辨症、辨证治疗基础上,结合病机及药性特点有针对性的选择对疾病的客观指标、病理改变等有明确治疗作用的中药,应用于处方中。该文以糖尿病为例,简述在不脱离中医背景的前提下如何实现现代药理研究成果的临床回归,以期对临床有所启发。
With the continuous enrichment of herbal pharmacology achievements,the effective components and the mechanism of many herbs have already been illustrated,which provides definite evidence for the treatment of modern diseases.However most herbal pharmacology achievements have not been used in clinic.Although some doctors have already taken advantage of the achievements consciously in clinical treatment,most prescriptions were still the simple addition of these achievements.The application of herbal pharmacology achievements cannot violate TCM theory.It should be considered on the basis of syndrome and symptoms differentiation.This passage takes diabetes for example to discuss the way of applying herbal pharmacology achievements in clinic without violating TCM theory.