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浙江名中医群治疗结直肠癌的中医思辨特征和共性规律研究
  • ISSN号:1005-5509
  • 期刊名称:《浙江中医药大学学报》
  • 时间:0
  • 分类:R574.6[医药卫生—消化系统;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]浙江中医药大学附属第一医院,杭州310006, [2]浙江省立同德医院, [3]浙江中医药大学
  • 相关基金:国家自然科学基金(81573902); 浙江省重大科技专项计划项目(2014C03036); 浙江省中医药科技计划(2014ZB029、2014ZA036)
中文摘要:

[目的]开展浙江名中医群治疗结直肠癌的中医思辨特征和共性规律研究,总结出名中医在结直肠癌诊疗中的群体共性规律。[方法]临床随诊在省内治疗结直肠癌有一定影响力的六位名中医(吴良村、郭勇、沈敏鹤、林胜友、冯正权、单泽松),规范采集和录入临床诊疗信息,建立名中医医案的数据库,根据数据挖掘的主题,建立相应的数据仓库,采用聚类分析、相关系数分析等数据挖掘技术,对各名中医的用药特点、辨证规律等进行数据的分析挖掘。[结果]六位医家在药物频数、药物性味、药物分类、高频药物聚类分析均有所不同,用药频数最高的分别为茯苓、甘草、太子参、黄连、白术和茯苓;吴良村、沈敏鹤、冯正权药物性味以平为主,而郭勇、林胜友、单泽松则以温性为主;六位医家都以甘味中药治疗结直肠癌;除林胜友以清热药为主外,其余五位医家均以补虚药治疗结直肠癌;吴良村高频药物以木香、黄连、地榆炭、马齿苋为主,沈敏鹤则以虎杖根、水杨梅根、藤梨根为主,郭勇以白术、茯苓、太子参、白芍、淡竹叶、荷叶、藤梨根、六神曲为主,林胜友以木香、黄连、大血藤、蒲公英、乌药为主,冯正权以生晒参片、白术、甘草、茯苓、陈皮、白芍、黄芩、厚朴为主,单泽松以茯苓、白术、党参、黄芪、干姜为主。[结论]六位医家对结直肠癌的处方用药,扶正为本,健脾为先,清化热毒,消积祛湿,辨证论治,善用药对。

英文摘要:

[Objective] To carry out the research on syndrome differentiation and their common law of colorectal cancer treatment of famous doctors of TCM in Zhejiang Province, and summarize the general law in their diagnosis and treatment. [Methods]We followed six doctors(WU Liangcun, GUO Yong, SHEN Minhe, LIN Shengyou, FENG Zhengquan and SHAN Zesong) who have the certain influence in treating colorectal cancer to learn their clinical experience,and then collected and input information of their clinical diagnosis and treatment regularly to establish the basis of traditional Chinese medicine record database according to the subject of data mining. We used cluster analysis, correlation analysis and other data mining technologies, to analyze their regularity of using drugs and syndrome differentiation. [Results]Six medical practitioners differ from each other in terms of drug frequency, drug property and flavor,classification of drug and cluster analysis of high-frequency drug, the drugs that are used the most frequently respectively: poria cocos, liquorice, radix pseudostellariae, coptis chinensis, rhizoma atractylodis and poria cocos; the drugs used by WU Liangcun, SHEN Minhe and FENG Zhengquan largely have a mild property and flavor, while the drugs used by GUO Yong, LIN Shenyou and SHAN Zesong largely have a warm property; all of the six medical practitioners use the traditional Chinese medicine of sweetish to treat the colorectal cancer; with the exception of LIN Shengyou who uses the heat-clearing drugs principally, all of the remaining five practitioners use the drugs of tonifying deficiency to treat the colorectal cancer.The high-frequency drugs of WU Liangcun are principally elecampane, coptis chinensis, carbonized sanguisorba root and purslane, the counterparts of SHEN Minhe are roots of polygonum cuspidatum, roots of fruit of thinleaf adina and Chinese actinidia root, the counterparts of GUO Yong are rhizoma atractylodis, poria cocos, radix pseudostellariae, radix paeoniae alba, lophatherum gracile, lotus leaf

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期刊信息
  • 《浙江中医药大学学报》
  • 中国科技核心期刊
  • 主管单位:浙江中医学院
  • 主办单位:浙江中医学院
  • 主编:方剑乔
  • 地址:杭州市滨江区滨文路548号
  • 邮编:310053
  • 邮箱:zjzyxb@163.com
  • 电话:0571-86613692
  • 国际标准刊号:ISSN:1005-5509
  • 国内统一刊号:ISSN:33-1349/R
  • 邮发代号:
  • 获奖情况:
  • 1989年获浙江省高校学报编辑质量三等奖,1990年获全国高等医药院校学报质量三等奖,1994年获浙江省高校学报二等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),波兰哥白尼索引,中国中国科技核心期刊
  • 被引量:14615