中文摘要：

为了赋予碳纳米管（CNTs）表面良好的生物性能，拓展CNTs在硬组织生物材料及组织工程支架材料中的应用，采用化学共沉淀和水热后处理法宏量制备了羟基磷灰石（HA）／多壁碳纳米管（MWCNTs）复合材料，通过调节制备过程中浓硝酸纯化的MWCNTs加入量，考察不同MWCNTs含量的HA／MWCNTs复合材料的结合形式．扫描电子显微镜（SEM）和透射电镜（TEM）表征结果表明，当ω（MWCNTs）=15％时，MWCNTs表面均匀地包覆了一层由纳米HA晶粒紧密相连的膜层，在此情况下MWCNTs与纳米HA形成最佳结合状态．体外细胞培养实验表明，制备的HA／MwCNTs复合材料具有良好的生物相容性．

英文摘要：

In order to get a good biological performance for carbon nanotubes, in this work, multi-walled carbon nano-tubes （MWC- NTs） were purified by the nitric acid,and purified MWCNTs were treated by a chemical coprecipitation of hydroxyapatite（HA） under the hydrothermal reaction. By changing the content of MWCNTs,a series of HA/MWCNTs composites with various percentages of MWCNTs were successfully prepared. The results characterized by SEM,TEM and spectroscopic measurements revealed that the MWCNTs could be well coated with a dense nano-hydroxyapatite coating when the content of MWCNTs was about 15 % （by mass）. In this case, the optimal combination between HA and MWCNTs can be achieved. In vitro cell culture demonstrates that the prepared HA/MWCNTs nano-composites with 15% （by mass） MWCNTs exhibit a good biocompatibility.