中文摘要：

如何优化慢性乙型肝炎患者的抗病毒疗效一直是临床研究的热点,近年来关于疗效预测的研究逐渐增加,主要包括HBs Ag、抗-HBc、ccc DNA、乙型肝炎病毒核心相关抗原和HBV RNA定量对临床疗效的预测研究,对这些指标的预测效果进行了综述。

英文摘要：

Optimization of antiviral effect in patients with chronic hepatitis B has always been a hot topic of clinical research. In recent years,more and more studies have focused on the prediction of antiviral effect,including the values of HBs Ag,anti-HBc,covalently closed circular DNA,HBcr Ag,and HBV RNA quantitation in predicting antiviral effect. This article reviews the predictive values of these markers.