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煎煮对几种特色南药中重金属元素含量和形态影响
  • ISSN号:1004-4957
  • 期刊名称:《分析测试学报》
  • 时间:0
  • 分类:O657.3[理学—分析化学;理学—化学] TQ460.72[医药卫生—药物分析学;化学工程—制药化工]
  • 作者机构:[1]中国广州分析测试中心广东省分析测试技术公共实验室,广东广州510070, [2]佛山科学技术学院食品科学与工程学院,广东佛山528000, [3]兰州理工大学石油化工学院,甘肃兰州730050
  • 相关基金:国家自然科学基金(21307120);广东省科技计划项目(20128061800043,20168020240006)
中文摘要:

考察了几种特色南药中重金属(Cd,Cr,Cu,Fe,Mn,Ni,Pb,Sr,Zn)的含量状况,并采用形态连续萃取法分析重金属在药材中的形态分布,研究了药材煎煮时药材中重金属的释放及煎煮过程对药材中重金属形态分布的影响。结果表明,几种南药中Cr,Pb,Zn的含量较高,且巴戟天中的重金属总量高于限量标准;原药材中Cr,Cu,Mn,Ni,Pb和Zn主要存在于有机态和残留态,Fe和Sr主要存在于残留态。煎煮使南药中大量重金属迁移到药汤中;药汤中Cu,Mn,Cr,Pb和Zn主要来自于其在药材中的可交换态、碳酸盐结合态和有机态,而药汤中Sr,Ni和Fe不仅包含其非残留态,更多来自于它们的残留态。为减少药汤中重金属,对于Cu,Mn,Cr,Pb和Zn既要控制在药材中的总量,且需降低它们在药材中的非残留态含量;对于Fe,Ni和Sr则主要是控制其在药材中的总量。

英文摘要:

The concentrations of heavy metals(Cd,Cr,Cu,Fe,Mn,Ni,Pb,Sr,Zn) in several South China Medicines were investigated,the speciation of heavy metals were analyzed by the continuous extraction method,and the impact of decoction on contents and speciation of heavy metals were also studied.The results showed that,the concentrations of Cr,Pb,Zn were high in several medical herbs,and the total concentrations of heavy metals in Morinda officinalis were higher than the values of the limit standard.Cr,Cu,Mn,Ni,Pb and Zn in raw medicinal herbs mainly existed as the organic fraction and residual fraction,Fe and Sr mainly existed as residual fraction.A large amount of heavy metals in South China Medicine released to the medicine soup by decocting.Cu,Mn,Cr,Pb and Zn in medicine soup mainly derived from the exchangeable,carbonate bound and organic speciation in the medicinal herbs.Sr,Ni and Fe in medicine soup mainly derived from their residual fraction.The total concentrations and non residual amounts of Cu,Mn,Cr,Pb and Zn were required to keep in control to reduce the concentrations of heavy metals in the medicine soup,and the total concentrations of Fe,Ni and Sr were required to be in control in minority herbs.

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期刊信息
  • 《分析测试学报》
  • 北大核心期刊(2011版)
  • 主管单位:广东省科学技术厅
  • 主办单位:中国分析测试协会 中国广州分析测试中心
  • 主编:陈小明
  • 地址:广州市先烈中路100号34栋B201中国广州分析测试中心内
  • 邮编:510070
  • 邮箱:fxcsxb@china.com
  • 电话:020- 37656606
  • 国际标准刊号:ISSN:1004-4957
  • 国内统一刊号:ISSN:44-1318/TH
  • 邮发代号:46-104
  • 获奖情况:
  • 获广东省第一、二届优秀期刊奖
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘(网络版),日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),英国英国皇家化学学会文摘,中国北大核心期刊(2000版)
  • 被引量:25362