中文摘要：

介绍了静电喷射制备微球、微粒的原理、装置及所用聚合物。总结了静电喷射制备微球、微粒的影响因素及所制备微球、微粒的用途。静电喷射制备微球、微粒的影响因素主要包括电压、聚合物溶液流量、聚合物溶液浓度及电导率。已通过静电喷射制备微球、微粒的聚合物有聚己内酯、聚乳酸、聚丙交酯乙交酯、聚膦腈、聚乙烯基吡咯烷酮、壳聚糖等，主要用于药物、蛋白质、酶等生物活性分子的包埋研究。

英文摘要：

The mechanics, apparatus and polymer used in the fabrication of microspheres and microparticles by electrospraying are introduced. Electrospraying variables that have effect on microspheres forming and the application of the microspheres and particles are summarized. Variables that have influence on fabrication of polymer microspheres and particles in electrosraying include voltage of electric field, flow rate of polymer solution, concentration and con- ductivity of polymer solution. Polymers used in fabrication of microspheres or particles by electrospraying are poly-cap- rolactone, poly（lactic acid）, poly （lactic-co-glycolic acid）, polyphosphazene, poly （vinylpyrrolidone）, chitosan, etc. They have many uses in investigation of encapsulating drug, protein, enzyme and other bioactive compounds.