中文摘要：

以双醋瑞因和大黄酸为原料，分别通过选择性水解及选择性乙酰化反应合成5-乙酰氧基-4-羟基-9，10-二氢-9，10-二氧代-2-蒽羧酸（1）和4-乙酰氧基-5-羟基-9，10-二氢-9，10-二氧代-2-蒽羧酸（2），其中1收率17．5％，纯度99．4％：2收率19．6％，纯度99．1％。结构均经^1H NMR、^13C NMR、红外光谱及质谱鉴定，HPLC行为与文献-致。

英文摘要：

5-Acetoxy-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid （1） was prepared via selective hydrolysis of diacerein with a yield of 17.5% and purity of 99.4%. 4-Acetoxy-5-hydroxy-9,10-dioxo-9,10- dihydroanthracene-2-carboxylic acid （2） was synthesized via selective acylation of rhein with a yield of 19.6 % and purity of 99.1%. Their chemical structures were confirmed via ^1H/^13C NMR, IR, MS and the HPLC information was consistent with the literature.