中文摘要：

采用活性跟踪法,对瑞香狼毒（Stellera chamaejasme L.）中的杀螨活性成分进行研究。从瑞香狼毒乙酸乙酯提取物中分离出对朱砂叶螨（Tetranychus cinnabarinus）具有较强触杀和内吸活性的化合物Ⅳ,通过核磁共振（1H NMR,13C NMR）、红外色谱（IR）等方法对化合物Ⅳ进行鉴定,确定该化合物为东莨菪内酯（scopoletin）。杀螨活性的测定结果表明,东莨菪内酯可能是瑞香狼毒中重要的杀螨活性物质。东莨菪内酯对朱砂叶螨触杀活性的半致死浓度（LC50）值为1.267mg·mL-1,内吸活性的LC50值为7.388mg·mL-1。

英文摘要：

Using the acaricidal activity to guide the isolation,the compound Ⅳ,which had the highest contact and systemic toxicity to Tetranychus cinnabarinus,was obtained from ethyl acetate extracts of roots of Stellera chamaejasme L. The structure of compound Ⅳ was established as scopoletin by analysis of NMR（1H NMR,13C NMR）and IR data. The results of acaricidal activity analysis showed that scopoletin may be the principal acaricidal substance in the ethyl acetate extracts of S. chamaejasme extracts. And the mean lethal concentrations（LC50）of scopoletin for contact and systemic toxicity were 1.267 and 7.388 mg · mL-1,respectively. Subsequently,compound Ⅳ was analyzed by NMR and IR methods,and its contact and systemic toxicity to mites were determined. In accordance with the spectral data（1H NMR,13C NMR and IR）of compound Ⅳ,the chemical compound was identified as scopoletin. Scopoletin may be the principal acaricidal substance in S. chamaejasme extracts. And the mean lethal concentrations（LC50）of scopoletin for contact and systemic toxicity were 1.267 and 7.388 mg · mL-1,respectively.