中文摘要：

与模型药装载的 chitosan microspheres，水杨酸盐分子，被准备，并且这种暂停的绝缘的光谱学被测量，同时，重要松驰为 microspheres 暂停被观察。由建模松驰分析，参数，能反映 microspheres 和连续媒介的性质，被获得。而且，在水的阶段的 microspheres 的释放进程被监视真实及时也就是，在每个阶段由分析参数的时间依赖者变化反映松驰特征和电的参数释放进程被检测。chitosan microspheres 的控制版本过程在水的阶段与水杨酸盐装载了的研究表演根据不同释放机制被划分成三个阶段。在版本阶段，在绝缘的分析和水杨酸盐的数量获得的阶段参数之间的量的关系在 microspheres 带了被导出，并且一个即时监视方法通过在测量并且分析绝缘的光谱学获得的不同时间在 microspheres 释放材料被建立。

英文摘要：

The chitosan microspheres loaded with model drug, salicylate molecular, are prepared, and the dielectric spectroscopy of this kind of suspension is measured, meanwhile a significant relaxation is observed for the microspheres suspension. By the modeling analyric of the relaxation, the parameters, which can reflect the properties of microspheres and continuous medium, are obtained. Furthermore, the releasing process of microspheres in aqueous phase is monitored real-timely, namely, by analyzing the rime-dependent variation of the parameters reflecting the relaxation characteristics and electrical parameters in each phase the releasing process is detected. The research shows that the controlled release process of chitosan microspheres loaded with salicylate in aqueous phase is divided into three phases according to different releasing mechanisms. At the release stage, the quantitative relation between the phase parameters obtained by dielectric analysis and the amount of the salicylate carded in microspheres was derived, and a real-time monitoring method was established through releasing material in the microspheres at different times obtained by measuring and analyzing the dielectric spectroscopy.