目的:优选复方芦荟丸的提取工艺。方法:以芦荟苷为对照品,采用HPLC法测定芦荟中芦荟苷的含量。采用正交试验设计,以芦荟苷的含量及出膏率为综合指标,考察醇浓度、加醇倍量、提取次数及提取时间的影响。结果:最佳提取工艺为以生药10倍量的70%乙醇回流提取2次,每次1h。结论:该提取工艺合理、稳定、可行,为复方制剂的制备工艺提供了科学依据。
Objective:To optimize alcohol extraction process of compound aloe pills.Methods:Aloin as reference to determine the content of aloevera glycosides by HPLC.It was investigated at alcohol concentration,the amount of alcohol,extraction times and extraction time,with aloin and a comprehensive cream as index by orthogonal experimental design.Results:The optimum extraction of crude drug 10 times the amount of 70% ethanol was extracted two times,each time 1h.Conclusion:The extraction process is reasonable,stable and viable to provide a test basis for compound preparation