中文摘要：

以HIV病毒中的TATA为识别位点，设计并合成了由四个N-甲基吡咯环和两个脂肪族氨基酸组成的聚酰胺类DNA识别分子——PyPyPyPyβCONH（CH2）6NH2．合成采用片段偶合的手段，利用卤仿反应和DCC／HOBT偶合反应，合成了含4个芳香杂环的聚酰胺，而且将含有两个游离氨基的脂肪族己二胺成功地接到了链尾．并用核磁共振谱和质谱对该化合物进行了表征．

英文摘要：

A DNA recognizing polyamides molecule, PyPyPyPyβDNH （CH2）6NH2 which contains four-rings of N-methylpyrrole and two amino acids moieties, was synthesized by the chloroform reaction and the DCC/HOBT coupling reaction, and an amino-group of 1, 6-Diaminohexane was successfully linked to the polyamide. The structure of the polyamide derivative was confirmed by NMR and MS spectra.