中文摘要：

乙型肝炎病毒（HBV）感染可导致慢性肝炎、肝硬化以及肝细胞癌等肝脏疾病。1,25-（OH）2D3是维生素D的活性形式,其通过与分布在细胞内的维生素D受体（VDR）结合而发挥免疫学功能。越来越多的研究表明,VDR的基因多态性与HBV感染后的慢性化及治疗密切相关。因此,该文就VDR基因多态性在乙型肝炎发展中的作用进行简要综述。

英文摘要：

Hepatitis B virus （HBV） infection may develop into chronic hepatitis, cirrhosis and hepatocel- lular carcinoma （HCC）. 1,25-dihydroxyvitamln D3 , which is the active form of vitamin D,it could combine with intraeellular vitamin D receptor （ VDR）, and develop immunological function. More and more studies have indicated that VDR gene polymorphism and HBV chrorficity infection and treatment are closely associated. Here is to make a review of the effect of VDR gene polymorphism in HBV infection.