中文摘要：

研究发现过敏性疾病与肠道菌群失调密切相关，其具体机制未明，西医学认为可能与树突状细胞等免疫细胞导致的肠道通透性增高、肠道屏障破坏相关。根据中医理论，可以认为与“肺脏受邪，传于大肠”，“脾脏受邪，营养受限，微环境骚动”和“肝脏受邪，风气内动，微环境骚动”3个原因相关，根本原因在于“邪气凑之，正气必虚”。结合中医体质学的4个基本原理“生命过程论”“形神构成论”“环境制约论”“禀赋遗传论”探讨肠道菌群研究给中医过敏体质研究带来的启示。

英文摘要：

Studies have shown that intestinal flora imbalance is closely related with allergic diseases,yet its specific mechanism remains unclear.Modern medicine considers that it may be associated with in-creased intestinal permeability and intestinal barrier disruption caused by dendritic cells and other im-mune cells.Traditional Chinese Medicine identifies three possible approaches,which are “Lungs invaded by evil passing to the large intestine”,“Spleen invaded by evil leading to restricted nutrition and dis-turbed microenvironment”and “Liver invaded by evil leading to stirred-up wind and disturbed microenvi-ronment”.The root cause is that “Pathogenic factor invades when Zheng Qi is deficient”.This paper ex-plores what intestinal flora research can bring to the allergic constitution study by combining the four fun-damental theories “Life course theory”,“Composition of form and spirit”,“Environmental constraint theory”,and “Theory of innate endowment”.