中文摘要：

核转录因子-κB（NF-κB）信号转导通路广泛存在于真核生物中，参与胚胎发育、炎症、免疫以及肿瘤的发生发展等多种生物进程。NF-κB 信号转导通路的异常激活与神经胶质瘤的生物学特性改变密切相关。研究 NF-κB 信号转导通路与胶质瘤增殖、侵袭、凋亡和血管新生的关系，将为神经胶质瘤的治疗提供新的思路和靶点。

英文摘要：

NF-κB signaling pathway is widely present in eukaryotes,and it is involved in many biologi-cal processes,such as embryonic development,inflammation,immunity,and tumor development.The abnor-mal activation of NF-κB signaling pathway is closely related to the biological characteristics of glioma.Investiga-ting the role of NF-κB signaling pathway in the glioma proliferation,invasion,apoptosis and angiogenesis will provide new ideas and targets for the treatment of glioma.