目的:考察边缘性人格障碍患者的工作记忆功能是否存在缺陷。方法:31名边缘性人格障碍患者和31名正常对照组受试完成了改良版N-back任务(0-back和2-back)。采用重复测量方差分析比较两组在工作记忆指标(反应时、总正确率及连续反应正确率)上的差异。结果:方差分析结果显示工作记忆负荷主效应显著,2-back任务的总正确率显著低于0-back任务;边缘性人格障碍组的连续正确反应率显著低于正常对照组,但连续正确反应率与冲动得分相关不显著。结论:边缘性人格障碍的工作记忆存在某些缺陷。
Objective: To examine whether there are deficits of working memory(WM) in patients with Borderline Personality Disorder(BPD) compared with healthy controls. Methods: A sample of 31 BPD patients and 31 healthy controls finished the modified N-back task(O-back and 2-the back), which measures working memory. Measurement indices of working memory(Reaction time, accuracy and continuous accuracy) were scored, and Repeated measures ANOVA were used to analyze the differences between BPD group and control group. Results: There was a main effect of WM load on accuracy, the accuracy of 2-back was significantly lower than that of O-back. The continuous accuracy of BPD group was significantly lower than that of control group. The continuous accuracy was not associated with the impulsive scores. Conclusion: Patients with BPD have deficits of working memory.