中文摘要：

现在的学习为胰岛素的控制版本在综合瞄准 thermosensitive hydrogel。根据一个修改方法， hydroxybutyl chitosan (HBC ) hydrogel 拥有了热敏感被准备它能在 25T 上形成 hydrogel 在

英文摘要：

Present study aims at synthesizing a thermosensitive hydrogel for controlled release of insulin. According to a modified method, hydroxybutyl chitosan （HBC） hydrogel possessed thermal sensitivity is prepared which can form hydrogel at over 25℃. The HBC hydrogel is non-cytotoxic to mice fibroblasts cells （L929）. Insulin is 100% entrapped in the hydrogel, 38% of which is released in vitro from the concentration of 5% hydrogel after 48 h, whereas by enzymolysis with lysozyme, 80% of the total insulin is released after 48h. This study suggests that HBC hydrogel could be utilized for controlled release of insulin in a non-invasive manner.