目的 探讨负性情绪与肺癌早期患者氩氦刀术后生活质量的相关性。方法 选取2012年3月~2013年5月就诊的早期肺癌行氩氦刀切除术患者136例,依据肿瘤病人生活质量评分表(QOL)结果将62例评分〉30分、生活质量较好的患者分为A组;74例评分〈30分、生活质量较差的患者分为B组。并于4周后依据治疗调理结果将B组74例又分为B1组(生活质量好转组)45例及B2组(生活质量未见好转组)29例。分别于患者术后及治疗干预4周后的抑郁自评量表(SDS)、焦虑自评量表(SAS)及症状评分量表(SS)进行测评。结果 B组患者的SDS、SAS及SS评分均低于A组,组间差异有统计学意义(均P〈0.05);B1组患者的SDS、SAS及SS评分均优于B2组,差异有统计学意义(均P〈0.05)。通过多因素相关性分析,患者的SDS及SAS评分与QOL评分呈明显负相关(r=-0.759、-0.338,均P〈0.05),与SS评分呈明显正相关(r=0.783、0.634,均P〈0.05)。结论 焦虑及抑郁等负性情绪对术后患者的生存质量带来极大的不利影响,积极改善相关负性情绪可明显提升患者生活质量。
Objective To explore the relation between negative emotions and life quality of patients with early lung cancer after cryosurgical. Methods 136 patients with early lung cancer after cryosurgical were divided into two groups ac- cording to the quality of life of cancer patients score sheet (QOL) results. 62 patients with quality of life score higher than 30 points were as group A. 74 patients with quality of life of not more than 30 points (control 30 points) were as group B. The patients of group B were divided into group B1 (quality of life improved group,45 cases) and group B2 (group did not improve the quality of life,29 cases) according to the results of the quality of life of cancer patients score sheet (QOL) 4 weeks after treatment. The Self-Depression Scale (SDS) scores, Self-Rating Anxiety Scale (SAS) score and symptom score (SS) of patients were detected postoperative and 4 weeks after surgery and therapeutic. Results The SDS, SAS and SS of group B after operation were worse than that of group A after operation. The difference was statisti- cally significant (P〈0.05). The SSD, SAS and SS of group B1 were better than that of group B2 4 weeks after surgery and therapeutic. The difference was statistically significant (P〈0.05). By multivariate analysis, there were negatively correlated with QOL (r=-0. 759,-0. 338, P〈0.05), and the SSD and SAS levels of patients were positively correla- ted with SS (r=0. 783,0. 634, P〈0.05). Conclusion The anxiety and depression and other negative emotions make tre- mendous adverse effect on the quality of life of patients, and improvement of the related negative emotions actively can significantly improve the quality of life for patients.