中文摘要：

以环十二酮为原料合成了cis-2-苯磺酰基-12-苄基环十二酮、2-苯磺酰基-12-溴代环十二酮和2,12-二苄基环十二酮,它们的结构通过^1H NMR,^13C NMR和元素分析表征.化合物4的晶体结构参数：C25H32O3S,Mr=412.57,三斜晶系,空间群P1,a=0.96531（4）nm,b=1.12703（5）nm,c=1.17486（5）nm,α=89.278（2）°,β=75.582（2）°,γ=65.385（2）°,V=1.11938（8）nm^3,Dc=1.224 g/cm^3,Z=2,F（000）=444,μ（Mo Kα）=0.167 mm^-1,S=1.038.化合物6的晶体结构参数：C18H25BrO3S,Mr=401.35,三斜晶系,空间群P1,a=0.77771（16）nm,b=1.0143（2）nm,c=1.2040（2）nm,α=89.46（3）°,β=80.13（3）°,γ=75.27（3）°,V=0.9044（3）nm^3,Dc=1.474 g/cm^3,Z=2,F（000）=416和μ（Mo Kα）=2.400 mm-1,S=1.042.cis-2-苯磺酰基-12-苄基环十二酮和cis-2-苯磺酰基-12-溴代环十二酮的X射线衍射结果表明,环十二酮母体骨架采取[3333]-2-酮构象,较小的取代基位于角顺位,较大的取代基位于边外向位.

英文摘要：

cis-2-Phenylsulfonyl-12-benzylcyclododecanone,2-phenylsulfonyl-12-bromocyclododecanone and 2,12-dibenzylcyclododecanone were synthesized though cyclododecanone as raw material,and their structures were confirmed by 1H NMR,13C NMR spectra and elemental analysis.Crystal data for 4： C25H32O3S,Mr=412.57,triclinic,space group P1,a=0.96531（4） nm,b=1.12703（5） nm,c=1.17486（5） nm,α=89.278（2）°,β=75.582（2）°,γ=65.385（2）°,V=1.11938（8） nm^3,Dc=1.224 g/cm^3,Z=2,F（000）=444 and μ（Mo Kα）=0.167 mm^-1,S=1.038.Crystal data for 6： C18H25BrO3S,Mr=401.35,triclinic,space group P1,a=0.77771（16） nm,b=1.0143（2） nm,c=1.2040（2） nm,α=89.46（3）°,β=80.13（3）°,γ=75.27（3）°,V=0.9044（3） nm^3,Dc=1.474 g/cm^3,Z=2,F（000）=416 and μ（Mo Kα）=2.400 mm^-1,S=1.042.The X-ray diffraction analysis of cis-2-phenylsulfonyl-12-benzylcyclododecanone and cis-2-phenylsulfonyl-12-bromocyclododecanone showed that their ring skeleton of cyclododecanone moiety took -2-one conformation,the smaller substituted group was at α-corner-syn,and the bigger one was at α-side-exo position.