中文摘要：

目的：探讨原发性高血压（ EH）患者外周血中L-选择素的表达及意义。方法以甘油醛-3-磷酸脱氢酶（ GAPDH）为内参，运用半定量逆转录聚合酶链式反应技术检测L-选择素在55例EH患者（ EH组）及48例体检健康者（对照组）外周血中的表达情况，应用多媒体图象分析软件（ Quantity One 4．5．0）进行灰度扫描。结果 EH 组L-选择素表达水平为（3．08±2．13），高于对照组的（1．28±0．69）（P ＜0．01）。结论L-选择素在EH外周血中表达增加，提示L-选择素可能与EH的发生有关。

英文摘要：

Objective To investigate the expression and significance of L-selectin in peripheral blood of pa-tients with essential hypertension （ EH） .Methods Glyceraldehyde 3 phosphate dehydrogenase was used as the in-ternal control .The expression of L-selectin in peripheral blood of 55 EH patients and 48 normal controls was detected by semi-quantitative reverse transcription PCR （ RT-PCR ） technology , and the multimedia image analysis software （ Quantity One 4.5.0） was used to perform a grayscale scanning .Results The expression of L-selectin in EH pa-tients was significantly higher than that in controls （3.08 ±2.13 vs 1.28 ±0.69,P〈0.01）.Conclusion The ex-pression of L-selectin is higher in EH patients ,which indicates that L-selectin may be related to the development of EH .