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海洛因依赖者认知功能障碍的WCST对照研究
  • ISSN号:1002-0829
  • 期刊名称:《上海精神医学》
  • 时间:0
  • 分类:R595.5[医药卫生—临床医学;医药卫生—内科学] R749.3[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]上海交通大学医学院附属精神卫生中心,201108
  • 相关基金:基金项目:上海市卫生局公共卫生学科带头人计划,项目编号:08GWD24,上海市精神卫生中心科研基金项目(编号:2006-21)
中文摘要:

目的采用威斯康星卡片分类测验(Wisconsin Card Sorting Test,WCST)分析海洛因依赖者认知功能损害情况。方法分别对60例住院脱毒治疗的海洛因依赖者与40例正常对照者进行WCST测验。结果与正常对照相比,海洛因依赖组WCST的总应答数(100.6±20.2)、完成分类数(5.4±1.4)、概念化水平百分数(87.9±13.0)%等测验值均较正常组差(海洛因依赖组60例,正常对照组40例,P〈0.05);男女海洛因依赖者WCST测验结果无显著差异;相关性分析发现海洛因依赖者年龄、受教育年限、用毒品年限、每日使用量与WCST测验结果之间没有显著相关性。结论海洛因依赖者存在认知功能损害,应对海洛因依赖者进行系统的康复治疗改善其认知功能预防复发。

英文摘要:

Objective: To assess the cognitive impairment in the patients with heroin dependence. Methods: 60 patients with heroin dependence conducted Wisconsin card sorting test (WCST) during inpatient detoxification and 40 normal controls conducted same test. Results:Significant differences were found between the two groups in the following areas (60 patients with heroin dependence, 40 normal controls, P 〈 0.05 ) : number of total responses ( 100. 6 ± 20.2 ), number of categories (5.4 ± 1.4 ), percentages of conceptive level (87.9± 13.0)%. However no differences were found between male and female heroin dependent patients in these aspects ( P 〉 0.05 ). The study did not found that the severity of cognitive impairment correlated with years of heroin dependence, quantity of heroin use ( P 〉 0. 05 ). Conclusion: Patients with heroin dependence present cognitive impairments that can be detected by WCST. Therefore a comprehensive drug rehabilitation program which target on improving cognition is needed to improve their cognitive function and prevent relapse for heroin dependent patients.

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期刊信息
  • 《上海精神医学》
  • 中国科技核心期刊
  • 主管单位:上海市卫生局
  • 主办单位:上海市精神卫生中心
  • 主编:
  • 地址:上海市宛平南路600号
  • 邮编:200030
  • 邮箱:sharp_submission@163.com
  • 电话:021-34773296
  • 国际标准刊号:ISSN:1002-0829
  • 国内统一刊号:ISSN:31-1564/R
  • 邮发代号:4-798
  • 获奖情况:
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  • 被引量:12876