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消渴健胃散治疗糖尿病性胃轻瘫疗效观察
  • ISSN号:1673-842X
  • 期刊名称:《辽宁中医药大学学报》
  • 时间:0
  • 分类:R587.1[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]兖矿集团总医院,山东邹城273500
  • 相关基金:兖矿集团资助课题【兖矿充2006(13)】
中文摘要:

目的:观察消渴健胃散对糖尿病性胃轻瘫的临床疗效,探讨消渴健胃散治疗糖尿病性胃轻瘫的作用机理。方法:60例患者分为治疗组和对照组,每4周为1个疗程,8周为1个总疗程。观察治疗前后的空腹血糖、糖化血红蛋白指标、胃排空指标(GET、AAV、AcF、AcA、MI)的变化。结果:治疗4周后,治疗组总有效率93.33%,优于对照组73.33%(P〈0.05)。治疗8周后,治疗组血糖水平、糖化血红蛋白均较治疗前明显降低,胃排空指标明显改善(GET降低,AAV、ACF、MI提高),经统计学处理差异具有显著性(P〈0.05,P〈0.01)。结论:消渴健胃散可明显改善糖尿病胃轻瘫的症状体征,缩短病程,具有降血糖和糖化血红蛋白含量、促进胃排空的作用。

英文摘要:

Objective: To observe the clinical effect of Xiaokejianwei powder on diabetic gastroparesis and explore the possible mechanism. Methods: 60 subjects with diabetic gastroparesis were randomly divided into the treatment group and the control group ( 30 patients per group ). The period of treatment was eight weeks. At the baseline and after the mediation, serum fasting blood glucose, glycosylated hemoglobin and the gastric emptying index ( GET, AAV, ACF, ACA, MI ) were deternined. Results: After 4 weeks of treatment, the total effective rate in treatment group( 93.33% ) were significantly higher than which of the control group( 73.33% ) (P〈0.05). After 8 weeks' mediation, the levels of serum fasting blood glucose, glycosylated hemoglobin were increased and the gastric emptying index were significantly improved in the treatment group compared with the control group ( P〈0.05, P〈0.01 ). Conclusion: Xiaokejianwei powder could decrease the level of serum fasting blood glucose and glycosylated hemoglobin, enhance the gastric emptying so as to ameliorate the symptoms and objective sign of diabetic gastroparesis and shorten the course of disease.

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期刊信息
  • 《辽宁中医药大学学报》
  • 中国科技核心期刊
  • 主管单位:辽宁省教育厅
  • 主办单位:辽宁中医药大学
  • 主编:张立德
  • 地址:沈阳市皇姑区崇山东路79号
  • 邮编:110847
  • 邮箱:zyxb@vip.163.com
  • 电话:024-31207232
  • 国际标准刊号:ISSN:1673-842X
  • 国内统一刊号:ISSN:21-1543/R
  • 邮发代号:8-179
  • 获奖情况:
  • 中国学术期刊(光盘版)优秀期刊,中国学术期刊综合评价数据库来源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,中国中国科技核心期刊
  • 被引量:28712