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中文摘要：
在研究了铜、铅、镉和锌4种单一因子对多刺裸腹溞（Moina macrocopa）急性毒性作用基础上,采用Marking 相加指数法研究了联合毒性效应.实验结果表明：4种重金属离子的毒性大小依次为Cd2＋＞Cu2＋＞Pb2＋＞Zn2＋,对多刺裸腹溞48h的LC50分别为0.0076mg/L,0.0306mg/L,0.0532mg/L,0.3568mg/L;Pb2＋-Cu2＋-Cd2＋、Pb2＋-Zn2＋-Cd2＋3种离子和Cu2＋-Pb2＋-cd2＋-Zn2＋4种离子共存时的毒性效应表现为拮抗作用;Cu2＋-Zn2＋-Cd2＋和Pb2＋-cu2＋-Zn2＋共存时的联合毒性较为复杂,三者浓度比1：1：1时表现为协同作用,而毒性比1∶1：1时在24h内表现为协同作用,至48h时为拮抗作用.
英文摘要：
The joint toxicity of heavy mental ions copper, lead, cadmium and zinc to Moina macrocopa was evaluated basing on acute toxicity of the four kinds of single-factor by using marking additive index method. The result showed that the toxicity sequence of four heavy metals to Moina macrocopa was Cd2＋ 〉 Cu2＋ 〉 Pb2 ＋ 〉 Zn2＋. The median lethal concentrations （LCso）of 48h for copper, lead, cadmium and zinc to Moina macrocopa were 0. 0076mg/L, 0. 0306mg/L, 0. 0532mg/L and 0. 3568mg/L, respectively. The toxicity of mixture Pb2 ＋- Cu2 ＋ - Cd2 ＋ , Pb2 ＋ - Zn2 ＋ - Cd2 ＋ and Cu2 ＋ - Pb2 ＋ - Cd2＋ - Zn2＋ showed to be antagonistic. The joint toxicity of Cu2 ＋ - Zn2 ＋ - Cd2 ＋ and Pb2 ＋ - Cu2 ＋- Zn2 ~ was complicated. When the concentration proportion of the three was 1 ： 1 ： 1, they were synergetic to each other; however, if their toxicity proportion was 1：1：1, they were synergetic at 24h, but antagonistic at 48h.
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