辅以增强型体外反搏和吸气阻力阀的主动按压放松心肺复苏术(AEI—CPR)可以达到较好的血流动力学效果,而不同的外力作用决定了其复苏效果的好坏.文中在已建立的AEI.CPR数学模型基础上,利用NP完全组合优化问题的有效算法——模拟退火算法,对AEI—CPR外力作用的多个控制参数进行了优化,其目标函数为冠脉灌注压的平均值.优化后的结果表明,当胸部按压的最大值为438N、主动放松的最大值为199N、下肢按压的最大值为390mmHg、按压频率为102min-1、下肢从小腿到髂部的按压时序分别为O.20、0.21、0.22S时,可达到较好的血流动力学效果.
Active compression-decompression cardiopulmonary resuscitation (CPR) with enhanced external counterpulsation and inspiratory impedance threshold valve, namely, AEI-CPR, helps to achieve excellent hemodynamic effect. However, the resuscitation effect is subjected to the influence of the external force. In this paper, an efficient algorithm for NP complete combinatorial optimization problem, namely, simulated annealing algorithm, is used to optimize the control parameters of the external force for AEI-CPR based on an established mathematical model, with the average coronary perfusion pressure as the objective function. Optimization results show that optimal hemodynamic effect can be achieved when the maximum chest compression, chest decompression and lower limbs compression are respectively 438 N, 199 N and 390mmHg with a frequency of 102 min-1, and when the compression on calf, thigh and hip is in a time sequence of 0. 20, 0. 21 and 0.22 s.