类胰岛素生长园子-I(IGF-I)是促合成代谢、促有丝分裂和抗细胞凋亡的因子。妊娠早期母猪体内有大量IGF-I表达,对胚胎发育有重要作用。营养水平影响IGF—I及其mRNA的表达。本文介绍了母猪卵巢、输卵管和子宫内IGF—I及其mRNA的表达特点,重点阐述了营养水平对母猪IGF—I及其mRNA表达的调榨与可能机制。
Insulin-like growth factor-I is an important mediator of anabolism, mitosis and apoptosis of cell. IGF-I is expressed in organism of sows or gilts, and involved in development of embryo during early gestation. Concentration of IGF-I and expression of IGF-I mRNA are affected by levels of nutrition. In this article, the expressive characters of IGF-I and IGF-I mRNA in ovary, oviduct and uterus of sows or gilts are reviewed, and the nutritional regulation on their expression and possible mechanism are emphasized. [Chinese Journal of Animal Nutrition, 2006,18(Suppl):341-346]