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食管癌^18氟-氟代脱氧葡萄糖PET/CT检查特征
  • ISSN号:1673-9752
  • 期刊名称:《中华消化外科杂志》
  • 时间:0
  • 分类:R733.4[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]宁波大学医学院附属医院影像科,315020, [2]第二军医大学附属长海医院核医学科,上海200433
  • 相关基金:上海市博士后科研资助计划面上项目(11R21410600);上海市卫生局科研项目(XBR2011040);浙江省医药卫生科技计划项目(2013KYA182)
中文摘要:

目的 总结食管癌^18氟-氟代脱氧葡萄糖(^18 F-FDG) PET/CT检查影像学特征,以及代谢参数与分期的关系.方法 回顾性分析2012年1月至2014年12月第二军医大学附属长海医院收治的53例食管癌患者的临床资料.患者行全身^18 F-FDG PET/CT检查.分析PET/CT检查图像特征,并以SUV 2.5为阈值,获得食管原发病灶的最大标准摄取值(SUVmax)、平均标准摄取值(SUVavg)、肿瘤代谢体积(MTV)、最大直径,计算病灶糖酵解总量(TLG);同时测量转移区域淋巴结和远处转移癌的SUVmax.正态分布的计量资料以x^-±s表示,组间比较采用独立样本t检验.偏态分布的计量资料以中位数M(Qn)表示,组间比较采用Mann-Whitney检验.结果 (1)肿瘤部位和体积:肿瘤位于食管颈段1例,胸上段16例,胸中段18例,胸下段13例,同时位于胸上段+胸中段2例,胸中段+胸下段3例.肿瘤体积:1.6 cm× 1.2 cm×2.2cm~6.5 cm×7.0cm×7.2 cm.肿瘤最大直径为(6.1 ±2.1)cm(2.5 ~11.2 cm).(2)PET/CT检查表现:食管原发病灶:96.2% (51/53)的患者食管局限性^18 F-FDG摄取值增高,伴管壁增厚;病灶与正常食管壁分界不清;病变段管腔狭窄.3.8% (2/53)的患者食管局部结节样^18 F-FDG摄取值增高,CT检查图像示管壁未见增厚.邻近结构:24.5% (13/53)的患者肿瘤侵犯周围组织器官.受侵犯组织器官^18F-FDG摄取值增高,与食管原发病灶分界不清.区域淋巴结:77.4% (41/53)的患者发生区域淋巴结转移.转移淋巴结^18 F-FDG摄取值增高.远处转移:26.4%(14/53)的患者发生远处转移,主要位于肝和肺.转移癌^18 F-FDG摄取值增高.(3)PET/CT检查代谢参数值:53例食管原发灶:肿瘤SUVmax为16.3 ±6.2(4.9~30.9),SUVavg为6.0 ±1.7(3.3 ~10.4),MTV为18.14 cm^3 (7.74 cm^3 ,28.89 cm^3) ,TLG为105.37 g(42.85 g,205.62 g).转移区域淋巴结:SUVmax为10.5 ±5.6(2.7 ~21.9).远处转移癌:SU

英文摘要:

Objective To summarize the imaging characteristics ship of Fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT examination in esophageal carcinoma and the relation between metabolic parameters and stage.Methods The clinical data of 53 patients with esophageal carcinoma who were admitted to the Changhai Hospital Affiliated to the Second Military Medical University between January 2012 and December 2014 were retrospectively analyzed.All the patients underwent ^18F-FDG PET/CT examination.The standardized uptake value 2.5 (SUV 2.5) was set as threshold value, and maximum SUV (SUVmax), average SUV (SUVavg), metabolic tumor volume (MTV) and maximum diameter of primary lesion were collected.The total lesion glycolysis (TLG) was calculated and SUVmax of lymph nodes in the metastasis area and distant metastasis carcinoma was measured.Measurement data with normal distribution were presented as x^- ± s, and comparison between groups was evaluated with an independent sample the t test.Skew distribution data were described as M(Qn), and comparison between groups was analyzed using the Mann-Whitney test.Results (1) Tumor location and volume: one tumor was located at the cervical portion of the esophagus, 16 at the upper thoracic portion, 18 at the mid-thoracic portion,13 at the lower thoracic portion, 2 at the upper thoracic portion and mid-thoracic portion and 3 at the mid-thoracic portion and the lower thoracic portion.Tumor volume was 1.6 cm × 1.2 cm × 2.2 cm-6.5 cm × 7.0 cm× 7.2 cm and maximum diameter of tumor was (6.1 ± 2.1) cm (range, 2.5-11.2 cm).(2) Performance of PET/CT examination: of 53 patients, 51 (96.2%) had ^18 F-FDG uptake increased, thickening esophageal wall, unclear boundary between lesions and normal tissues and luminal stenosis of the lesion, and 2 (3.8%) had local nodular 18F-FDG uptake increased without thickening esophageal wall.The infringement of the surrounding tissue organs was detected in 13 patients (24.5%), with unclear boundary betwe

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期刊信息
  • 《中华消化外科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:
  • 地址:重庆沙坪坝区高滩岩30号
  • 邮编:400038
  • 邮箱:digsurg@263.net
  • 电话:023-68754655
  • 国际标准刊号:ISSN:1673-9752
  • 国内统一刊号:ISSN:11-5610/R
  • 邮发代号:78-117
  • 获奖情况:
  • 科技期刊论文统计源,中国科技核心期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,中国中国科技核心期刊,中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:8916